Chiisanoside Mediates the Parkin/ZNF746/PGC-1α Axis by Downregulating MiR-181a to Improve Mitochondrial Biogenesis in 6-OHDA-Caused Neurotoxicity Models In Vitro and In Vivo: Suggestions for Prevention of Parkinson’s Disease

The degeneration of dopamine (DA) neurons is known to be associated with defects in mitochondrial biogenesis caused by aging, environmental factors, or mutations in genes, leading to Parkinson’s disease (PD). As PD has not yet been successfully cured, the strategy of using small molecule drugs to pr...

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Detalles Bibliográficos
Autores principales: Hsu, Yu-Ling, Chen, Hui-Jye, Gao, Jia-Xin, Yang, Ming-Yang, Fu, Ru-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525196/
https://www.ncbi.nlm.nih.gov/pubmed/37760085
http://dx.doi.org/10.3390/antiox12091782

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525196/
https://www.ncbi.nlm.nih.gov/pubmed/37760085
http://dx.doi.org/10.3390/antiox12091782

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