Substrate Stiffness Modulates TGF-β Activation and ECM-Associated Gene Expression in Fibroblasts

Transforming growth factor-β (TGF-β) is a multifunctional cytokine that regulates the expression of ECM-associated genes during early injury. Tissue fibrosis development is driven by synergistic cues between the evolving biochemical and mechanical milieu. Few studies have addressed the role of subst...

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Detalles Bibliográficos
Autores principales: Verma, Brijesh Kumar, Chatterjee, Aritra, Kondaiah, Paturu, Gundiah, Namrata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525202/
https://www.ncbi.nlm.nih.gov/pubmed/37760100
http://dx.doi.org/10.3390/bioengineering10090998

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525202/
https://www.ncbi.nlm.nih.gov/pubmed/37760100
http://dx.doi.org/10.3390/bioengineering10090998

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