Non-Lethal Doses of RSL3 Impair Microvascular Endothelial Barrier through Degradation of Sphingosie-1-Phosphate Receptor 1 and Cytoskeletal Arrangement in A Ferroptosis-Independent Manner

The excess microvascular endothelial permeability is a hallmark of acute inflammatory diseases. Maintenance of microvascular integrity is critical to preventing leakage of vascular components into the surrounding tissues. Sphingosine-1-phosphate (S1P) is an active lysophospholipid that enhances the...

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Detalles Bibliográficos
Autores principales: Baoyinna, Boina, Miao, Jiaxing, Oliver, Patrick J., Ye, Qinmao, Shaheen, Nargis, Kalin, Timothy, He, Jinshan, Parinandi, Narasimham L., Zhao, Yutong, Zhao, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525432/
https://www.ncbi.nlm.nih.gov/pubmed/37760892
http://dx.doi.org/10.3390/biomedicines11092451

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525432/
https://www.ncbi.nlm.nih.gov/pubmed/37760892
http://dx.doi.org/10.3390/biomedicines11092451

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