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A Comparative Study on Cyclodextrin Derivatives in Improving Oral Bioavailability of Etoricoxib as a Model Drug: Formulation and Evaluation of Solid Dispersion-Based Fast-Dissolving Tablets

Etoricoxib, as a model drug, has a poor solubility and dissolution rate. Cyclodextrin derivatives can be used to solve such a problem. A comparative study was run on three cyclodextrin derivatives, namely β-CD, HP β-CD, and SBE β-CD, to solve the drug problem through the formulation of solid dispers...

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Detalles Bibliográficos
Autores principales: Elsegaie, Doaa, El-Nabarawi, Mohamed A., Mahmoud, Hanaa Abdelmonem, Teaima, Mahmoud, Louis, Dina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525456/
https://www.ncbi.nlm.nih.gov/pubmed/37760881
http://dx.doi.org/10.3390/biomedicines11092440