Expanding the MAPPs Assay to Accommodate MHC-II Pan Receptors for Improved Predictability of Potential T Cell Epitopes

SIMPLE SUMMARY: The major histocompatibility complex class II-associated peptide proteomics assay is widely used during preclinical immunogenicity risk assessments to identify biotherapeutic-derived peptides. These potential T cell epitopes are presented by dendritic cells and may trigger CD4(+) T h...

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Detalles Bibliográficos
Autores principales: Hartman, Katharina, Steiner, Guido, Siegel, Michel, Looney, Cary M., Hickling, Timothy P., Bray-French, Katharine, Springer, Sebastian, Marban-Doran, Céline, Ducret, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525474/
https://www.ncbi.nlm.nih.gov/pubmed/37759665
http://dx.doi.org/10.3390/biology12091265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525474/
https://www.ncbi.nlm.nih.gov/pubmed/37759665
http://dx.doi.org/10.3390/biology12091265

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