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Modelling the Decamerisation Cycle of PRDX1 and the Inhibition-like Effect on Its Peroxidase Activity

Peroxiredoxins play central roles in the detoxification of reactive oxygen species and have been modelled across multiple organisms using a variety of kinetic methods. However, the peroxiredoxin dimer-to-decamer transition has been underappreciated in these studies despite the 100-fold difference in...

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Detalles Bibliográficos
Autores principales: Barry, Christopher J., Pillay, Ché S., Rohwer, Johann M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525498/
https://www.ncbi.nlm.nih.gov/pubmed/37760010
http://dx.doi.org/10.3390/antiox12091707