Cargando…
Modelling the Decamerisation Cycle of PRDX1 and the Inhibition-like Effect on Its Peroxidase Activity
Peroxiredoxins play central roles in the detoxification of reactive oxygen species and have been modelled across multiple organisms using a variety of kinetic methods. However, the peroxiredoxin dimer-to-decamer transition has been underappreciated in these studies despite the 100-fold difference in...
Autores principales: | Barry, Christopher J., Pillay, Ché S., Rohwer, Johann M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525498/ https://www.ncbi.nlm.nih.gov/pubmed/37760010 http://dx.doi.org/10.3390/antiox12091707 |
Ejemplares similares
-
Structural basis of peroxidase catalytic cycle of human Prdx6
por: Chowhan, Rimpy Kaur, et al.
Publicado: (2020) -
The peroxidase PRDX1 inhibits the activated phenotype in mammary fibroblasts through regulating c-Jun N-terminal kinases
por: Jezierska-Drutel, Agnieszka, et al.
Publicado: (2019) -
Physiological Functions of Thiol Peroxidases (Gpx1 and Prdx2) during Xenopus laevis Embryonic Development
por: Lee, Hongchan, et al.
Publicado: (2021) -
PRDX2 removal inhibits the cell cycle and autophagy in colorectal cancer cells
por: Zheng, Xiangru, et al.
Publicado: (2020) -
Prdx1 inhibits tumorigenesis via regulating PTEN/AKT activity
por: Cao, Juxiang, et al.
Publicado: (2009)