Progress towards the Replacement of the Rabbit Blood Sugar Test for the Quantitative Determination of the Biological Activity of Insulins (USP <121>) with an In Vitro Assay

SIMPLE SUMMARY: The recent United States Pharmacopeia general chapter <121> requires a non-quantitative bioidentity test either as a rabbit blood sugar assay or as an in vitro insulin cell-based assay using in-cell Western (ICW) technology for insulin batch release. However, for quantification...

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Detalles Bibliográficos
Autores principales: Rüggeberg, Sabrina, Wanglin, Antje, Demirel, Özlem, Hack, Rüdiger, Niederhaus, Birgit, Bidlingmaier, Bernd, Blumrich, Matthias, Usener, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525547/
https://www.ncbi.nlm.nih.gov/pubmed/37760353
http://dx.doi.org/10.3390/ani13182953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525547/
https://www.ncbi.nlm.nih.gov/pubmed/37760353
http://dx.doi.org/10.3390/ani13182953

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