Oxidative and Endoplasmic Reticulum Stress Represent Novel Therapeutic Targets for Choroideremia

Choroideremia (CHM) is a rare X-linked chorioretinal dystrophy, affecting the photoreceptors, retinal pigment epithelium (RPE) and choroid, with no approved therapy. CHM is caused by mutations in the CHM gene, which encodes the ubiquitously expressed Rab escort protein 1 (REP1). REP1 is involved in...

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Detalles Bibliográficos
Autores principales: Sarkar, Hajrah, Lahne, Manuela, Nair, Neelima, Moosajee, Mariya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525549/
https://www.ncbi.nlm.nih.gov/pubmed/37759997
http://dx.doi.org/10.3390/antiox12091694

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525549/
https://www.ncbi.nlm.nih.gov/pubmed/37759997
http://dx.doi.org/10.3390/antiox12091694

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