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The Antimalarial Drug Artesunate Mediates Selective Cytotoxicity by Upregulating HO-1 in Melanoma Cells

Despite great efforts to develop new therapeutic strategies to combat melanoma, the prognosis remains rather poor. Artesunate (ART) is an antimalarial drug displaying anti-cancer effects in vitro and in vivo. In this in vitro study, we investigated the selectivity of ART on melanoma cells. Furthermo...

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Detalles Bibliográficos
Autores principales: Jochims, Finn, Strohm, Rebecca, von Montfort, Claudia, Wenzel, Chantal-Kristin, Klahm, Niklas, Kondadi, Arun Kumar, Stahl, Wilhelm, Reichert, Andreas S., Brenneisen, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525565/
https://www.ncbi.nlm.nih.gov/pubmed/37760834
http://dx.doi.org/10.3390/biomedicines11092393