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Virtual Screening of Potential RoxS Inhibitors and Evaluation of Their Antimicrobial Activity in Combination with Antibiotics against Clinically Resistant Bacteria

Pseudomonas aeruginosa with difficult-to-treat resistance has been designated as an urgent or serious threat by the CDC in the United States; therefore, novel antibacterial drugs and combination strategies are urgently needed. The sensor kinase RoxS is necessary for the aerobic growth of Pseudomonas...

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Detalles Bibliográficos
Autores principales: Huang, Ya-Yan, Li, Jia-Hao, Liang, Ting-Ting, Zhao, Ze-An, Xu, Jun, Chen, Wen-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525716/
https://www.ncbi.nlm.nih.gov/pubmed/37760718
http://dx.doi.org/10.3390/antibiotics12091422