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Homogeneous Space Construction and Projection for Single-Cell Expression Prediction Based on Deep Learning

Predicting cellular responses to perturbations is an unsolved problem in biology. Traditional approaches assume that different cell types respond similarly to perturbations. However, this assumption does not take into account the context of genome interactions in different cell types, which leads to...

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Detalles Bibliográficos
Autores principales: Yeh, Chia-Hung, Chen, Ze-Guang, Liou, Cheng-Yue, Chen, Mei-Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525719/
https://www.ncbi.nlm.nih.gov/pubmed/37760098
http://dx.doi.org/10.3390/bioengineering10090996