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Uncovering the Early Events Associated with Oligomeric Aβ-Induced Src Activation

Soluble Aβ(1–42) oligomers (AβO) are formed in the early stages of Alzheimer’s disease (AD) and were previously shown to trigger enhanced Ca(2+) levels and mitochondrial dysfunction via the activation of N-methyl-D-aspartate receptors (NMDAR). Src kinase is a ubiquitous redox-sensitive non-receptor...

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Detalles Bibliográficos
Autores principales: Mota, Sandra I., Fão, Lígia, Coelho, Patrícia, Rego, A. Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525724/
https://www.ncbi.nlm.nih.gov/pubmed/37760073
http://dx.doi.org/10.3390/antiox12091770