PGC-1α Agonist Rescues Doxorubicin-Induced Cardiomyopathy by Mitigating the Oxidative Stress and Necroptosis

Cardiomyopathy (particularly dilated cardiomyopathy (DCM)) significantly contributes to development and progression of heart failure (HF), and inflammatory factors further deteriorate the symptoms. Morphological and functional defects of the heart in doxorubicin (DOX)-induced cardiomyopathy (cardiot...

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Detalles Bibliográficos
Autores principales: Shipra, Tembhre, Manoj Kumar, Hote, Milind Padmakar, Bhari, Neetu, Lakshmy, Ramakrishnan, Kumaran, S. Senthil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525725/
https://www.ncbi.nlm.nih.gov/pubmed/37760023
http://dx.doi.org/10.3390/antiox12091720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525725/
https://www.ncbi.nlm.nih.gov/pubmed/37760023
http://dx.doi.org/10.3390/antiox12091720

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