Toward Ameliorating Insulin Resistance: Targeting a Novel PAK1 Signaling Pathway Required for Skeletal Muscle Mitochondrial Function

The p21-activated kinase 1 (PAK1) is required for insulin-stimulated glucose uptake in skeletal muscle cells. However, whether PAK1 regulates skeletal muscle mitochondrial function, which is a central determinant of insulin sensitivity, is unknown. Here, the effect of modulating PAK1 levels (knockdo...

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Detalles Bibliográficos
Autores principales: Balakrishnan, Rekha, Garcia, Pablo A., Veluthakal, Rajakrishnan, Huss, Janice M., Hoolachan, Joseph M., Thurmond, Debbie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525748/
https://www.ncbi.nlm.nih.gov/pubmed/37759961
http://dx.doi.org/10.3390/antiox12091658

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525748/
https://www.ncbi.nlm.nih.gov/pubmed/37759961
http://dx.doi.org/10.3390/antiox12091658

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