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Cytocompatibility and Osteoinductive Properties of Collagen-Fibronectin Hydrogel Impregnated with siRNA Targeting Glycogen Synthase Kinase 3β: In Vitro Study

In this study, we developed an osteoplastic material based on collagen–fibronectin hydrogel impregnated with siRNA molecules targeting glycogen synthase kinase 3β (GSK3β), which inhibits the osteogenic differentiation of mesenchymal stem cells. The hydrogel impregnated with polyplexes containing siR...

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Detalles Bibliográficos
Autores principales: Galitsyna, Elena V., Buianova, Anastasiia A., Kozhukhov, Vadim I., Domogatsky, Sergey P., Bukharova, Tatiana B., Goldshtein, Dmitriy V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525875/
https://www.ncbi.nlm.nih.gov/pubmed/37760805
http://dx.doi.org/10.3390/biomedicines11092363