Cargando…

Cytocompatibility and Osteoinductive Properties of Collagen-Fibronectin Hydrogel Impregnated with siRNA Targeting Glycogen Synthase Kinase 3β: In Vitro Study

In this study, we developed an osteoplastic material based on collagen–fibronectin hydrogel impregnated with siRNA molecules targeting glycogen synthase kinase 3β (GSK3β), which inhibits the osteogenic differentiation of mesenchymal stem cells. The hydrogel impregnated with polyplexes containing siR...

Descripción completa

Detalles Bibliográficos
Autores principales:	Galitsyna, Elena V., Buianova, Anastasiia A., Kozhukhov, Vadim I., Domogatsky, Sergey P., Bukharova, Tatiana B., Goldshtein, Dmitriy V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525875/ https://www.ncbi.nlm.nih.gov/pubmed/37760805 http://dx.doi.org/10.3390/biomedicines11092363

Ejemplares similares

Osteoinductive Moldable and Curable Bone Substitutes Based on Collagen, BMP-2 and Highly Porous Polylactide Granules, or a Mix of HAP/β-TCP
por: Vasilyev, Andrey Vyacheslavovich, et al.
Publicado: (2021)

Collagen as Bioink for Bioprinting: A Comprehensive Review
por: Osidak, Egor Olegovich, et al.
Publicado: (2020)

Hydrothermal Transformation of Eggshell Calcium Carbonate into Apatite Micro-Nanoparticles: Cytocompatibility and Osteoinductive Properties
por: Torres-Mansilla, Adriana, et al.
Publicado: (2023)

Design of an Osteoinductive Extracellular Fibronectin Matrix Protein for Bone Tissue Engineering
por: Lee, Sujin, et al.
Publicado: (2015)

Simple application of adipose-derived stem cell-derived extracellular vesicles coating enhances cytocompatibility and osteoinductivity of titanium implant
por: Chen, Lifeng, et al.
Publicado: (2020)

Osteogenic Differentiation of Human Adipose Tissue-Derived MSCs by Non-Toxic Calcium Poly(ethylene phosphate)s
por: Nifant’ev, Ilya, et al.
Publicado: (2019)

Glycogen Synthase Kinase-3
por: Crouch, Peter, et al.
Publicado: (2011)

Control of Glycogen Content in Retina: Allosteric Regulation of Glycogen Synthase
por: Osorio-Paz, Ixchel, et al.
Publicado: (2012)

Biomaterial osteoinduction
por: Nakamura, Takashi
Publicado: (2007)

Comparative Efficiency of Gene-Activated Matrices Based on Chitosan Hydrogel and PRP Impregnated with BMP2 Polyplexes for Bone Regeneration
por: Nedorubova, Irina Alekseevna, et al.
Publicado: (2022)

Mechanism of glycogen synthase inactivation and interaction with glycogenin
por: Marr, Laura, et al.
Publicado: (2022)

Interactomes of Glycogen Synthase Kinase-3 Isoforms
por: Cormier, Kevin W., et al.
Publicado: (2023)

Glycogen Synthase Kinase-3 Is Required for Efficient Dictyostelium Chemotaxis
por: Teo, Regina, et al.
Publicado: (2010)

Hexokinase 2, Glycogen Synthase and Phosphorylase Play a Key Role in Muscle Glycogen Supercompensation
por: Irimia, José M., et al.
Publicado: (2012)

Glycogen synthase kinase 3β in tumorigenesis and oncotherapy
por: He, Rui, et al.
Publicado: (2020)

Bacterial Cellulose (Komagataeibacter rhaeticus) Biocomposites and Their Cytocompatibility
por: Petrova, Valentina A., et al.
Publicado: (2020)

Inhibition of Glycogen Synthase II with RNAi Prevents Liver Injury in Mouse Models of Glycogen Storage Diseases
por: Pursell, Natalie, et al.
Publicado: (2018)

In Vitro Effects of Strontium on Proliferation and Osteoinduction of Human Preadipocytes
por: Nardone, V., et al.
Publicado: (2015)

A Crosstalk between the Biorhythms and Gatekeepers of Longevity: Dual Role of Glycogen Synthase Kinase-3
por: Shilovsky, Gregory A., et al.
Publicado: (2021)

Hepatic glycogen synthase (GYS2) deficiency: seven novel patients and seven novel variants
por: Kamenets, Elena A., et al.
Publicado: (2020)

Glycogen Synthase Kinase-3 in the Etiology and Treatment of Mood Disorders
por: Jope, Richard Scott
Publicado: (2011)

Glycogen Synthase Kinase-3 is an Intermediate Modulator of Serotonin Neurotransmission
por: Polter, Abigail M., et al.
Publicado: (2011)

The Effects of Glycogen Synthase Kinase-3beta in Serotonin Neurons
por: Zhou, Wenjun, et al.
Publicado: (2012)

Glycogen Synthase Kinase 3β in Cancer Biology and Treatment
por: Domoto, Takahiro, et al.
Publicado: (2020)

Glycogen Synthase Kinase 3: Ion Channels, Plasticity, and Diseases
por: Marosi, Mate, et al.
Publicado: (2022)

The role of glycogen synthase kinase 3 beta in neurodegenerative diseases
por: Yu, Honglu, et al.
Publicado: (2023)

Hypoxia Promotes Glycogen Accumulation through Hypoxia Inducible Factor (HIF)-Mediated Induction of Glycogen Synthase 1
por: Pescador, Nuria, et al.
Publicado: (2010)

A novel mutation in the glycogen synthase 2 gene in a child with glycogen storage disease type 0
por: Soggia, Ana Priscila, et al.
Publicado: (2010)

Glycogen Synthase Isoforms in Synechocystis sp. PCC6803: Identification of Different Roles to Produce Glycogen by Targeted Mutagenesis
por: Yoo, Sang-Ho, et al.
Publicado: (2014)

Circadian clock regulation of the glycogen synthase (gsn) gene by WCC is critical for rhythmic glycogen metabolism in Neurospora crassa
por: Baek, Mokryun, et al.
Publicado: (2019)

Glycogen synthase kinase-3: a new therapeutic target in renal cell carcinoma
por: Bilim, V, et al.
Publicado: (2009)

Aberrant expression of glycogen synthase kinase-3β in human breast and head and neck cancer
por: Ugolkov, Andrey V., et al.
Publicado: (2018)

Therapeutic ultrasound in fracture healing: The mechanism of osteoinduction
por: John, P S, et al.
Publicado: (2008)

Engineering of immunoinstructive extracellular matrices for enhanced osteoinductivity
por: García-García, Andrés, et al.
Publicado: (2022)

Quantification of the glycogen cascade system: the ultrasensitive responses of liver glycogen synthase and muscle phosphorylase are due to distinctive regulatory designs
por: Mutalik, Vivek K, et al.
Publicado: (2005)

Glucose-6-Phosphate–Mediated Activation of Liver Glycogen Synthase Plays a Key Role in Hepatic Glycogen Synthesis
por: von Wilamowitz-Moellendorff, Alexander, et al.
Publicado: (2013)

Biophysical Characterization and Cytocompatibility of Cellulose Cryogels Reinforced with Chitin Nanowhiskers
por: Tyshkunova, Irina V., et al.
Publicado: (2022)

Antidiabetic and vasoprotective activity of lithium: Role of glycogen synthase kinase-3
por: Kanzariya, Nilesh R., et al.
Publicado: (2011)

Functional Implications of Glycogen Synthase Kinase-3-Mediated Tau Phosphorylation
por: Hanger, Diane P., et al.
Publicado: (2011)

Regulation by Glycogen Synthase Kinase-3 of Inflammation and T Cells in CNS Diseases
por: Beurel, Eléonore
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_62fdaqu474b14svjdl4rh69429