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Redox Regulation of Nrf2 in Cisplatin-Induced Kidney Injury

Cisplatin, a potent chemotherapeutic agent, is marred by severe nephrotoxicity that is governed by mechanisms involving oxidative stress, inflammation, and apoptosis pathways. The transcription factor Nrf2, pivotal in cellular defense against oxidative stress and inflammation, is the master regulato...

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Detalles Bibliográficos
Autores principales: Mapuskar, Kranti A., Pulliam, Casey F., Zepeda-Orozco, Diana, Griffin, Benjamin R., Furqan, Muhammad, Spitz, Douglas R., Allen, Bryan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525889/
https://www.ncbi.nlm.nih.gov/pubmed/37760031
http://dx.doi.org/10.3390/antiox12091728