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Geranylgeranylacetone Ameliorates Skin Inflammation by Regulating and Inducing Thioredoxin via the Thioredoxin Redox System

Geranylgeranylacetone (GGA) exerts cytoprotective activity against various toxic stressors via the thioredoxin (TRX) redox system; however, its effect on skin inflammation and molecular mechanism on inducing the TRX of GGA is still unknown. We investigated the effects of GGA in a murine irritant con...

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Detalles Bibliográficos
Autores principales: Jin, Tiancheng, You, Yitong, Fan, Wenjie, Wang, Junyang, Chen, Yuhao, Li, Shujing, Hong, Siyuan, Wang, Yaxuan, Cao, Ruijie, Yodoi, Junji, Tian, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525896/
https://www.ncbi.nlm.nih.gov/pubmed/37760004
http://dx.doi.org/10.3390/antiox12091701