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Engineering and Purification of Microcin C7 Variants Resistant to Trypsin and Analysis of Their Biological Activity

Microcin C7 (McC) as a viable form of antimicrobial has gained substantial attention due to its distinctive antimicrobial activity, by targeting aspartyl tRNA synthetase. McC can be a potential solution against pathogenic microbial infections in the postantibiotic era. However, considering that degr...

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Detalles Bibliográficos
Autores principales: Yang, Guangxin, Shang, Lijun, Liu, Lu, Li, Zeqiang, Zeng, Xiangfang, Ding, Xiuliang, Huang, Jinxiu, Qiao, Shiyan, Yu, Haitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525924/
https://www.ncbi.nlm.nih.gov/pubmed/37760643
http://dx.doi.org/10.3390/antibiotics12091346