First Generation of Antioxidant Precursors for Bioisosteric Se-NSAIDs: Design, Synthesis, and In Vitro and In Vivo Anticancer Evaluation

The introduction of selenium (Se) into organic scaffolds has been demonstrated to be a promising framework in the field of medicinal chemistry. A novel design of nonsteroidal anti-inflammatory drug (NSAID) derivatives based on a bioisosteric replacement via the incorporation of Se as diacyl diseleni...

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Detalles Bibliográficos
Autores principales: Ramos-Inza, Sandra, Aliaga, Cesar, Encío, Ignacio, Raza, Asif, Sharma, Arun K., Aydillo, Carlos, Martínez-Sáez, Nuria, Sanmartín, Carmen, Plano, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525927/
https://www.ncbi.nlm.nih.gov/pubmed/37759969
http://dx.doi.org/10.3390/antiox12091666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525927/
https://www.ncbi.nlm.nih.gov/pubmed/37759969
http://dx.doi.org/10.3390/antiox12091666

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