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Hyperinflammatory Immune Response in COVID-19: Host Genetic Factors in Pyrin Inflammasome and Immunity to Virus in a Spanish Population from Majorca Island

The hyperinflammatory response caused by SARS-CoV-2 infection contributes to its severity, and many critically ill patients show features of cytokine storm (CS) syndrome. We investigated, by next-generation sequencing, 24 causative genes of primary immunodeficiencies whose defect predisposes to CS....

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Detalles Bibliográficos
Autores principales: Martínez-Pomar, Natalia, Cunill, Vanesa, Segura-Guerrero, Marina, Pol-Pol, Elisabet, Escobar Oblitas, Danilo, Pons, Jaime, Ayestarán, Ignacio, Pruneda, Patricia C., Losada, Inés, Toledo-Pons, Nuria, García Gasalla, Mercedes, Ferrer Balaguer, Joana Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525993/
https://www.ncbi.nlm.nih.gov/pubmed/37760989
http://dx.doi.org/10.3390/biomedicines11092548