Profiling the Biophysical Developability Properties of Common IgG1 Fc Effector Silencing Variants

Therapeutic antibodies represent the most significant modality in biologics, with around 150 approved drugs on the market. In addition to specific target binding mediated by the variable fragments (Fvs) of the heavy and light chains, antibodies possess effector functions through binding of the const...

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Detalles Bibliográficos
Autores principales: Pejchal, Robert, Cooper, Anthony B., Brown, Michael E., Vásquez, Maximiliano, Krauland, Eric M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526015/
https://www.ncbi.nlm.nih.gov/pubmed/37753968
http://dx.doi.org/10.3390/antib12030054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526015/
https://www.ncbi.nlm.nih.gov/pubmed/37753968
http://dx.doi.org/10.3390/antib12030054

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