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Profiling the Biophysical Developability Properties of Common IgG1 Fc Effector Silencing Variants
Therapeutic antibodies represent the most significant modality in biologics, with around 150 approved drugs on the market. In addition to specific target binding mediated by the variable fragments (Fvs) of the heavy and light chains, antibodies possess effector functions through binding of the const...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526015/ https://www.ncbi.nlm.nih.gov/pubmed/37753968 http://dx.doi.org/10.3390/antib12030054 |