Long-Term L-Glutamine Treatment Reduces Hemolysis without Ameliorating Hepatic Vaso-Occlusion and Liver Fibrosis in a Mouse Model of Sickle Cell Disease

Sickle cell disease (SCD) is an autosomal recessive monogenic disorder caused by a homozygous mutation in the β-globin gene, which leads to erythrocyte sickling, hemolysis, vaso-occlusion, and sterile inflammation. The administration of oral L-glutamine has been shown to reduce the frequency of pain...

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Detalles Bibliográficos
Autores principales: Katoch, Omika, Ungalara, Ramakrishna, Kaminski, Tomasz, Li, Ziming, Dubey, Rikesh K., Burholt, Isabella, Gudapati, Shweta, Pradhan-Sundd, Tirthadipa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526062/
https://www.ncbi.nlm.nih.gov/pubmed/37760853
http://dx.doi.org/10.3390/biomedicines11092412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526062/
https://www.ncbi.nlm.nih.gov/pubmed/37760853
http://dx.doi.org/10.3390/biomedicines11092412

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