Persistent Hypoxia with Intermittent Aggravation Causes Imbalance in Smad3/Myocardin-Related Transcription Factor Signaling with Consequent Endothelial Senescence and Pulmonary Arterial Remodeling

Loss of Smad3 and the consequent activation of myocardin-related transcription factor (MRTF) are associated with vascular pathologies. This study aimed to examine the impact of persistent hypoxia with intermittent aggravation (PI hypoxia) on cellular senescence and pulmonary arterial remodeling medi...

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Detalles Bibliográficos
Autores principales: Hu, Jiaxin, Singh, Prachi, Li, Jingrui, Zhang, Jing, Li, Fei, Zhang, Hehe, Xie, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526072/
https://www.ncbi.nlm.nih.gov/pubmed/37760802
http://dx.doi.org/10.3390/biomedicines11092351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526072/
https://www.ncbi.nlm.nih.gov/pubmed/37760802
http://dx.doi.org/10.3390/biomedicines11092351

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