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Promoter Optimization Circumvents Bcl-2 Transgene-Mediated Suppression of Lentiviral Vector Production

Lentiviral vectors are a robust gene delivery tool for inducing transgene expression in a variety of cells. They are well suited to facilitate the testing of therapeutic candidate genes in vitro, due to relative ease of packaging and ability to transduce dividing and non-dividing cells. Our goal was...

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Detalles Bibliográficos
Autores principales: Kok, Cindy Y., MacLean, Lauren M., Rao, Renuka, Tsurusaki, Shinya, Kizana, Eddy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526134/
https://www.ncbi.nlm.nih.gov/pubmed/37759797
http://dx.doi.org/10.3390/biom13091397