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Differential Gene Expression in Activated Microglia Treated with Adenosine A(2A) Receptor Antagonists Highlights Olfactory Receptor 56 and T-Cell Activation GTPase-Activating Protein 1 as Potential Biomarkers of the Polarization of Activated Microglia

Microglial activation often accompanies the plastic changes occurring in the brain of patients with neurodegenerative diseases. A(2A) and A(3) adenosine receptors have been proposed as therapeutic targets to combat neurodegeneration. RNAseq was performed using samples isolated from lipopolysaccharid...

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Detalles Bibliográficos
Autores principales: Lillo, Alejandro, Serrano-Marín, Joan, Lillo, Jaume, Raïch, Iu, Navarro, Gemma, Franco, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526142/
https://www.ncbi.nlm.nih.gov/pubmed/37759436
http://dx.doi.org/10.3390/cells12182213