Cargando…
Differential Gene Expression in Activated Microglia Treated with Adenosine A(2A) Receptor Antagonists Highlights Olfactory Receptor 56 and T-Cell Activation GTPase-Activating Protein 1 as Potential Biomarkers of the Polarization of Activated Microglia
Microglial activation often accompanies the plastic changes occurring in the brain of patients with neurodegenerative diseases. A(2A) and A(3) adenosine receptors have been proposed as therapeutic targets to combat neurodegeneration. RNAseq was performed using samples isolated from lipopolysaccharid...
Autores principales: | Lillo, Alejandro, Serrano-Marín, Joan, Lillo, Jaume, Raïch, Iu, Navarro, Gemma, Franco, Rafael |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526142/ https://www.ncbi.nlm.nih.gov/pubmed/37759436 http://dx.doi.org/10.3390/cells12182213 |
Ejemplares similares
-
Expression of the Adenosine A(2A)-A(3) Receptor Heteromer in Different Brain Regions and Marked Upregulation in the Microglia of the Transgenic APP(Sw,Ind) Alzheimer’s Disease Model
por: Lillo, Alejandro, et al.
Publicado: (2022) -
Antagonization of OX(1) Receptor Potentiates CB(2) Receptor Function in Microglia from APP(Sw/Ind) Mice Model
por: Raïch, Iu, et al.
Publicado: (2022) -
The olfactory Olfr-78/51E2 receptor interacts with the adenosine A(2A) receptor. Effect of menthol and 1,8-cineole on A(2A) receptor-mediated signaling
por: Lillo, Jaume, et al.
Publicado: (2023) -
Methamphetamine Blocks Adenosine A(2A) Receptor Activation via Sigma 1 and Cannabinoid CB(1) Receptors
por: Casanovas, Mireia, et al.
Publicado: (2021) -
Ghrelin and Cannabinoid Functional Interactions Mediated by Ghrelin/CB(1) Receptor Heteromers That Are Upregulated in the Striatum From Offspring of Mice Under a High-Fat Diet
por: Lillo, Alejandro, et al.
Publicado: (2021)