Systematic Exploration of Functional Group Relevance for Anti-Leishmanial Activity of Anisomycin

Assessment of structure–activity relationships for anti-protozoan activity revealed a strategy for preparing potent anisomycin derivatives with reduced host toxicity. Thirteen anisomycin analogs were synthesized by modifying the alcohol, amine, and aromatic functional groups. Examination of anti-pro...

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Detalles Bibliográficos
Autores principales: Nguyen, Anh Minh Thao, Shalev-Benami, Moran, Rosa-Teijeiro, Chloé, Ibarra-Meneses, Ana Victoria, Yonath, Ada, Bashan, Anat, Jaffe, Charles L., Olivier, Martin, Fernandez-Prada, Christopher, Lubell, William D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526209/
https://www.ncbi.nlm.nih.gov/pubmed/37760981
http://dx.doi.org/10.3390/biomedicines11092541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526209/
https://www.ncbi.nlm.nih.gov/pubmed/37760981
http://dx.doi.org/10.3390/biomedicines11092541

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