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Targeted Strategies for Degradation of Key Transmembrane Proteins in Cancer

Targeted protein degradation is an attractive technology for cancer treatment due to its ability to overcome the unpredictability of the small molecule inhibitors that cause resistance mutations. In recent years, various targeted protein degradation strategies have been developed based on the ubiqui...

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Detalles Bibliográficos
Autores principales: Sakanyan, Vehary, Iradyan, Nina, Alves de Sousa, Rodolphe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526213/
https://www.ncbi.nlm.nih.gov/pubmed/37754201
http://dx.doi.org/10.3390/biotech12030057