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The Avidity of Autoreactive Alpha-Synuclein Antibodies in Leucine-Rich Repeat Kinase 2 Mutation Carriers Is Not Altered Compared to Healthy Controls or Patients with Parkinson’s Disease

The accumulation and aggregation of alpha-synuclein (α-Syn) are pathological processes associated with Parkinson’s disease, indicating that the regulation of protein is a crucial etiopathological mechanism. Interestingly, human serum and cerebrospinal fluid contain autoantibodies that recognize α-Sy...

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Detalles Bibliográficos
Autores principales: Albus, Alexandra, Kronimus, Yannick, Burg-Roderfeld, Monika, van der Wurp, Hendrik, Willbold, Dieter, Ziehm, Tamar, Dodel, Richard, Ross, Jean Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526238/
https://www.ncbi.nlm.nih.gov/pubmed/37759704
http://dx.doi.org/10.3390/biom13091303