Indomethacin Induces Spermidine/Spermine-N(1)-Acetyltransferase-1 via the Nucleolin-CDK1 Axis and Synergizes with the Polyamine Oxidase Inhibitor Methoctramine in Lung Cancer Cells

Indomethacin is a non-selective NSAID used against pain and inflammation. Although cyclooxygenase (COX) inhibition is considered indomethacin’s primary action mechanism, COX-independent ways are associated with beneficial effects in cancer. In colon cancer cells, the activation of the peroxisome pro...

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Detalles Bibliográficos
Autores principales: Buelvas, Neudo, Ugarte-Vio, Isidora, Asencio-Leal, Laura, Muñoz-Uribe, Matías, Martin-Martin, Antonia, Rojas-Fernández, Alejandro, Jara, José A., Tapia, Julio C., Arias, María Elena, López-Muñoz, Rodrigo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526249/
https://www.ncbi.nlm.nih.gov/pubmed/37759783
http://dx.doi.org/10.3390/biom13091383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526249/
https://www.ncbi.nlm.nih.gov/pubmed/37759783
http://dx.doi.org/10.3390/biom13091383

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