Multi-Omics Analyses Reveal Mitochondrial Dysfunction Contributing to Temozolomide Resistance in Glioblastoma Cells

Glioblastoma (GBM) is the most common and aggressive malignant brain tumor with poor prognosis. Temozolomide (TMZ) is the standard chemotherapy for glioblastoma treatment, but TMZ resistance significantly compromises its efficacy. In the present study, we generated a TMZ-resistant cell line and iden...

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Detalles Bibliográficos
Autores principales: Zhang, Huaijin, Chen, Yuling, Liu, Xiaohui, Deng, Haiteng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526285/
https://www.ncbi.nlm.nih.gov/pubmed/37759808
http://dx.doi.org/10.3390/biom13091408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526285/
https://www.ncbi.nlm.nih.gov/pubmed/37759808
http://dx.doi.org/10.3390/biom13091408

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