Cargando…

Multi-Omics Analyses Reveal Mitochondrial Dysfunction Contributing to Temozolomide Resistance in Glioblastoma Cells

Glioblastoma (GBM) is the most common and aggressive malignant brain tumor with poor prognosis. Temozolomide (TMZ) is the standard chemotherapy for glioblastoma treatment, but TMZ resistance significantly compromises its efficacy. In the present study, we generated a TMZ-resistant cell line and iden...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Huaijin, Chen, Yuling, Liu, Xiaohui, Deng, Haiteng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526285/ https://www.ncbi.nlm.nih.gov/pubmed/37759808 http://dx.doi.org/10.3390/biom13091408

Ejemplares similares

Mitochondrial dysfunction contributes to Rapamycin-induced apoptosis of Human Glioblastoma Cells - A synergistic effect with Temozolomide
por: Zimmerman, Mary A, et al.
Publicado: (2020)

Temozolomide resistance in glioblastoma multiforme
por: Lee, Sang Y.
Publicado: (2016)

Celecoxib reverses the glioblastoma chemo-resistance to temozolomide through mitochondrial metabolism
por: Yin, Delong, et al.
Publicado: (2021)

Exosomal transfer of miR-1238 contributes to temozolomide-resistance in glioblastoma
por: Yin, Jianxing, et al.
Publicado: (2019)

An overview of glioblastoma multiforme and temozolomide resistance: can LC-MS-based proteomics reveal the fundamental mechanism of temozolomide resistance?
por: Teraiya, Milan, et al.
Publicado: (2023)

Interplay of m(6)A and histone modifications contributes to temozolomide resistance in glioblastoma
por: Li, Fuxi, et al.
Publicado: (2021)

SOCS5 contributes to temozolomide resistance in glioblastoma by regulating Bcl-2-mediated autophagy
por: Yu, Jie, et al.
Publicado: (2022)

Potential Strategies Overcoming the Temozolomide Resistance for Glioblastoma
por: JIAPAER, Shabierjiang, et al.
Publicado: (2018)

Interfering with mitochondrial dynamics sensitizes glioblastoma multiforme to temozolomide chemotherapy
por: Wang, Nan, et al.
Publicado: (2021)

Tbx2 confers poor prognosis in glioblastoma and promotes temozolomide resistance with change of mitochondrial dynamics
por: Yi, Fuxin, et al.
Publicado: (2017)

Olaparib Is a Mitochondrial Complex I Inhibitor That Kills Temozolomide-Resistant Human Glioblastoma Cells
por: Zampieri, Luca X., et al.
Publicado: (2021)

Multi-Omics Analysis Reveals Novel Subtypes and Driver Genes in Glioblastoma
por: Yuan, Yang, et al.
Publicado: (2020)

Relation between autophagy and the resistence of glioblastoma cells to temozolomide
por: Carmo, Anália, et al.
Publicado: (2010)

Integrins and p53 pathways in glioblastoma resistance to temozolomide
por: Martin, Sophie, et al.
Publicado: (2012)

Metformin treatment reduces temozolomide resistance of glioblastoma cells
por: Yang, Seung Ho, et al.
Publicado: (2016)

Mechanisms of temozolomide resistance in glioblastoma - a comprehensive review
por: Singh, Neha, et al.
Publicado: (2021)

Temozolomide Resistance in Glioblastoma by NRF2: Protecting the Evil
por: Almeida Lima, Karoline, et al.
Publicado: (2023)

Multi-Omics Analyses Reveal Systemic Insights into Maize Vivipary
por: Wang, Yiru, et al.
Publicado: (2021)

GENETIC SCREENING REVEALS DEPENDENCY ON FEN1 TO RESIST TEMOZOLOMIDE IN TREATMENT-RESISTANT GLIOBLASTOMA STEM CELLS
por: Brakel, Benjamin, et al.
Publicado: (2023)

Human forebrain organoids-based multi-omics analyses reveal PCCB’s regulation on GABAergic system contributing to schizophrenia
por: Zhang, Wendiao, et al.
Publicado: (2023)

Molecular Mechanisms of KDELC2 on Glioblastoma Tumorigenesis and Temozolomide Resistance
por: Tsai, Yu-Ling, et al.
Publicado: (2020)

Gossypol Suppresses Growth of Temozolomide-Resistant Glioblastoma Tumor Spheres
por: Kim, Hee Yeon, et al.
Publicado: (2019)

Nanomedicine-based combination therapies for overcoming temozolomide resistance in glioblastomas
por: Wang, Chun, et al.
Publicado: (2023)

Multi-omics analyses of CD276 in pan-cancer reveals its clinical prognostic value in glioblastoma and other major cancer types
por: Dai, Lirui, et al.
Publicado: (2023)

Reprogramming of arachidonate metabolism confers temozolomide resistance to glioblastoma through enhancing mitochondrial activity in fatty acid oxidation
por: Tsai, Yu-Ting, et al.
Publicado: (2022)

SH3GLB1-related autophagy mediates mitochondrial metabolism to acquire resistance against temozolomide in glioblastoma
por: Chien, Chia-Hung, et al.
Publicado: (2022)

Multi-omics analysis reveals that ornithine decarboxylase contributes to erlotinib resistance in pancreatic cancer cells
por: Jang, Won-Jun, et al.
Publicado: (2017)

Revealing the epigenetic effect of temozolomide on glioblastoma cell lines in therapeutic conditions
por: Belter, Agnieszka, et al.
Publicado: (2020)

Cationic gold nanoparticles elicit mitochondrial dysfunction: a multi-omics study
por: Gallud, Audrey, et al.
Publicado: (2019)

Multi-omics analyses of human colorectal cancer revealed three mitochondrial genes potentially associated with poor outcomes of patients
por: Zhang, Wei, et al.
Publicado: (2021)

Multi-omics analyses reveal ClpP activators disrupt essential mitochondrial pathways in triple-negative breast cancer
por: Fennell, Emily M. J., et al.
Publicado: (2023)

SPDR-05 PARP INHIBITORS RESTORE TEMOZOLOMIDE SENSITIVITY IN MSH6-DEFICIENT TEMOZOLOMIDE-RESISTANT GLIOBLASTOMA CELLS
por: Higuchi, Fumi, et al.
Publicado: (2019)

A novel 3D in vitro model of glioblastoma reveals resistance to temozolomide which was potentiated by hypoxia
por: Musah-Eroje, Ahmed, et al.
Publicado: (2019)

Accelerated hyperfractionation plus temozolomide in glioblastoma
por: Kaul, David, et al.
Publicado: (2016)

Strategies of temozolomide in future glioblastoma treatment
por: Lee, Chooi Yeng
Publicado: (2017)

Temozolomide antagonizes oncolytic immunovirotherapy in glioblastoma
por: Saha, Dipongkor, et al.
Publicado: (2020)

ATP7B expression in human glioblastoma is related to temozolomide resistance
por: Moinuddin, F.M., et al.
Publicado: (2017)

LAPTM5–CD40 Crosstalk in Glioblastoma Invasion and Temozolomide Resistance
por: Berberich, Anne, et al.
Publicado: (2020)

Identification of a transient state during the acquisition of temozolomide resistance in glioblastoma
por: Rabé, Marion, et al.
Publicado: (2020)

Inhibition of Carbonic Anhydrase 2 Overcomes Temozolomide Resistance in Glioblastoma Cells
por: Zhao, Kai, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_2k4r4ukge7jg9ujsr86fed1ter