Dual Targeting of EZH2 Degradation and EGFR/HER2 Inhibition for Enhanced Efficacy against Burkitt’s Lymphoma

SIMPLE SUMMARY: Burkitt’s lymphoma (BL) is an aggressive type of non-Hodgkin lymphoma that originates from B-cells. It is characterized by translocation of the MYC gene, leading to the upregulation of this gene and subsequently causing overexpression of EZH2. Since BL shows rapid involvement, the de...

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Detalles Bibliográficos
Autores principales: Kim, Se Been, Yang, Chae-Eun, Jeong, Yurim, Yu, Minseo, Choi, Wan-Su, Lim, Jung-Yeon, Jeon, Youngwoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526300/
https://www.ncbi.nlm.nih.gov/pubmed/37760442
http://dx.doi.org/10.3390/cancers15184472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526300/
https://www.ncbi.nlm.nih.gov/pubmed/37760442
http://dx.doi.org/10.3390/cancers15184472

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