Diabetes-Induced Amplification of Nociceptive DRG Neuron Output by Upregulation of Somatic T-Type Ca(2+) Channels

The development of pain symptoms in peripheral diabetic neuropathy (PDN) is associated with the upregulation of T-type Ca(2+) channels (T-channels) in the soma of nociceptive DRG neurons. Moreover, a block of these channels in DRG neurons effectively reversed mechanical and thermal hyperalgesia in a...

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Detalles Bibliográficos
Autores principales: Ivasiuk, Arsentii, Matvieienko, Maksym, Kononenko, Nikolai I., Duzhyy, Dmytro E., Korogod, Sergiy M., Voitenko, Nana, Belan, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526307/
https://www.ncbi.nlm.nih.gov/pubmed/37759720
http://dx.doi.org/10.3390/biom13091320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526307/
https://www.ncbi.nlm.nih.gov/pubmed/37759720
http://dx.doi.org/10.3390/biom13091320

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