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Functional Distinctions of Endometrial Cancer-Associated Mutations in the Fibroblast Growth Factor Receptor 2 Gene

Functional analysis of somatic mutations in tumorigenesis facilitates the development and optimization of personalized therapy for cancer patients. The fibroblast growth factor receptor 2 (FGFR2) gene is frequently mutated in endometrial cancer (EC), but the functional implications of FGFR2 mutation...

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Detalles Bibliográficos
Autores principales: Dixit, Garima, Pappas, Benjamin A., Bhardwaj, Gourav, Schanz, Willow, Maretzky, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526318/
https://www.ncbi.nlm.nih.gov/pubmed/37759450
http://dx.doi.org/10.3390/cells12182227