Transition Mutations in the hTERT Promoter Are Unrelated to Potential i-motif Formation in the C-Rich Strand

Increased expression of the human telomere reverse transcriptase (hTERT) in tumors promotes tumor cell survival and diminishes the survival of patients. Cytosine-to-thymine (C-to-T) transition mutations (C250T or C228T) in the hTERT promoter create binding sites for transcription factors, which enha...

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Detalles Bibliográficos
Autores principales: Conrad, James W., Sowers, Mark L., Yap, Dianne Y., Cherryhomes, Ellie, Pettitt, B. Montgomery, Khanipov, Kamil, Sowers, Lawrence C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526324/
https://www.ncbi.nlm.nih.gov/pubmed/37759708
http://dx.doi.org/10.3390/biom13091308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526324/
https://www.ncbi.nlm.nih.gov/pubmed/37759708
http://dx.doi.org/10.3390/biom13091308

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