A Closed Loop Stimuli-Responsive Concanavalin A-Loaded Chitosan–Pluronic Hydrogel for Glucose-Responsive Delivery of Short-Acting Insulin Prototyped in RIN-5F Pancreatic Cells

The optimal treatment of diabetes (in particular, type 1 diabetes—T1D) remains a challenge. Closed-loop systems (implants/inserts) provide significant advantages for glucose responsivity and providing real-time sustained release of rapid-acting insulin. Concanavalin A (ConA), a glucose affinity agen...

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Detalles Bibliográficos
Autores principales: Mansoor, Shazia, Adeyemi, Samson A., Kondiah, Pierre P. D., Choonara, Yahya E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526345/
https://www.ncbi.nlm.nih.gov/pubmed/37760986
http://dx.doi.org/10.3390/biomedicines11092545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526345/
https://www.ncbi.nlm.nih.gov/pubmed/37760986
http://dx.doi.org/10.3390/biomedicines11092545

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