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Single-Step IGHV Next-Generation Sequencing Detects Clonality and Somatic Hypermutation in Lymphoid Malignancies: A Phase III Diagnostic Accuracy Study

SIMPLE SUMMARY: Clonality testing and somatic hypermutation analysis performed on B-cell receptor encoding genes are the most widely used molecular assays for lymphoma diagnostics. Currently, PCR-based methods standardized by the BIOMED2 consortium are regarded as the gold standard. In the last few...

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Detalles Bibliográficos
Autores principales: Gazzola, Anna, Navari, Mohsen, Mannu, Claudia, Donelli, Riccardo, Etebari, Maryam, Piccaluga, Pier Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526376/
https://www.ncbi.nlm.nih.gov/pubmed/37760593
http://dx.doi.org/10.3390/cancers15184624