The Impact of Drug–Drug Interactions on the Toxicity Profile of Combined Treatment with BRAF and MEK Inhibitors in Patients with BRAF-Mutated Metastatic Melanoma

SIMPLE SUMMARY: Drug–drug interactions (DDIs) risk is quite common, potentially significant, and often underestimated. In this context, an advanced DDI detection software (Drug-PIN, V. 2/23) was used to assess the DDIs in a retrospective cohort of 177 patients with metastatic BRAF-mutated cutaneous...

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Detalles Bibliográficos
Autores principales: Mezi, Silvia, Botticelli, Andrea, Scagnoli, Simone, Pomati, Giulia, Fiscon, Giulia, De Galitiis, Federica, Di Pietro, Francesca Romana, Verkhovskaia, Sofia, Amirhassankhani, Sasan, Pisegna, Simona, Gentile, Giovanna, Simmaco, Maurizio, Gohlke, Bjoern, Preissner, Robert, Marchetti, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526382/
https://www.ncbi.nlm.nih.gov/pubmed/37760556
http://dx.doi.org/10.3390/cancers15184587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526382/
https://www.ncbi.nlm.nih.gov/pubmed/37760556
http://dx.doi.org/10.3390/cancers15184587

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