AAV-Mediated Targeting of the Activin A-ACVR1(R206H) Signaling in Fibrodysplasia Ossificans Progressiva

Fibrodysplasia ossificans progressiva (FOP) is an ultra-rare genetic disorder characterized by progressive disabling heterotopic ossification (HO) at extra-skeletal sites. Here, we developed adeno-associated virus (AAV)-based gene therapy that suppresses trauma-induced HO in FOP mice harboring a het...

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Detalles Bibliográficos
Autores principales: Yang, Yeon-Suk, Lin, Chujiao, Ma, Hong, Xie, Jun, Kaplan, Frederick S., Gao, Guangping, Shim, Jae-Hyuck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526456/
https://www.ncbi.nlm.nih.gov/pubmed/37759764
http://dx.doi.org/10.3390/biom13091364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526456/
https://www.ncbi.nlm.nih.gov/pubmed/37759764
http://dx.doi.org/10.3390/biom13091364

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