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Repurposing Clemastine to Target Glioblastoma Cell Stemness

SIMPLE SUMMARY: Brain tumor-initiating cells (BTICs) drive tumor progression and resistance to treatments, posing formidable challenges to advancing effective treatments against glioblastoma (GBM). We postulated that inducing BTIC differentiation can serve as a solution to diminishing their malignan...

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Detalles Bibliográficos
Autores principales: Sun, Michael A., Yang, Rui, Liu, Heng, Wang, Wenzhe, Song, Xiao, Hu, Bo, Reynolds, Nathan, Roso, Kristen, Chen, Lee H., Greer, Paula K., Keir, Stephen T., McLendon, Roger E., Cheng, Shi-Yuan, Bigner, Darell D., Ashley, David M., Pirozzi, Christopher J., He, Yiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526458/
https://www.ncbi.nlm.nih.gov/pubmed/37760589
http://dx.doi.org/10.3390/cancers15184619