Inhibition of Dipeptidyl Peptidase-4 Activates Autophagy to Promote Survival of Breast Cancer Cells via the mTOR/HIF-1α Pathway

SIMPLE SUMMARY: The prevalence of certain cancers is high in the diabetic population. Dipeptidyl peptidase (DPP)-4, a therapeutic target for type 2 diabetes mellitus, is also involved in autophagic flux and cancer biology. In this paper, we reported that DPP-4 inhibition promotes breast cancer cell...

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Detalles Bibliográficos
Autores principales: Kawakita, Emi, Yang, Fan, Shi, Sen, Takagaki, Yuta, Koya, Daisuke, Kanasaki, Keizo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526496/
https://www.ncbi.nlm.nih.gov/pubmed/37760498
http://dx.doi.org/10.3390/cancers15184529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526496/
https://www.ncbi.nlm.nih.gov/pubmed/37760498
http://dx.doi.org/10.3390/cancers15184529

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