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Myeloid Cell Leukemia 1 Small Molecule Inhibitor S63845 Synergizes with Cisplatin in Triple-Negative Breast Cancer

SIMPLE SUMMARY: This manuscript builds on our recent observations that the cell-death-suppressing protein, MCL1, is able to directly regulate the DNA damage response transcription factor TP73. TP73, a homolog of TP53, is known to be activated following treatment with the anti-cancer drug, cisplatin....

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Detalles Bibliográficos
Autores principales: Acton, Alexus, Placzek, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526511/
https://www.ncbi.nlm.nih.gov/pubmed/37760451
http://dx.doi.org/10.3390/cancers15184481