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Conditional Knockout of N-WASP Enhanced the Formation of Keratinizing Squamous Cell Carcinoma Induced by KRas(G12D)

SIMPLE SUMMARY: The expression of N-WASP (Neural Wiskott-Aldrich Syndrome Protein) is found to be reduced in certain human cancers, and this has been associated with poor prognoses for patients. To characterize the role of N-WASP in the tumorigenesis of squamous cell carcinoma (SCC), we generated mi...

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Detalles Bibliográficos
Autores principales: Kalailingam, Pazhanichamy, Verma, Apoorva, Lee, Ying Hui, Thanabalu, Thirumaran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526518/
https://www.ncbi.nlm.nih.gov/pubmed/37760426
http://dx.doi.org/10.3390/cancers15184455