Establishing the Link between X-Chromosome Aberrations and TP53 Status, with Breast Cancer Patient Outcomes

Ubiquitous to normal female human somatic cells, X-chromosome inactivation (XCI) tightly regulates the transcriptional silencing of a single X chromosome from each pair. Some genes escape XCI, including crucial tumour suppressors. Cancer susceptibility can be influenced by the variability in the gen...

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Detalles Bibliográficos
Autores principales: Caramia, Franco, Speed, Terence P., Shen, Hui, Haupt, Ygal, Haupt, Sue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526523/
https://www.ncbi.nlm.nih.gov/pubmed/37759468
http://dx.doi.org/10.3390/cells12182245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526523/
https://www.ncbi.nlm.nih.gov/pubmed/37759468
http://dx.doi.org/10.3390/cells12182245

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