Nuclear translocation of thioredoxin-1 promotes colorectal cancer development via modulation of the IL-6/STAT3 signaling axis through interaction with STAT3

Background: Thioredoxin 1 (Trx-1) is a small redox protein predominantly localized in the cytoplasm. Its expression is increased in several cancers, including colorectal cancer (CRC). However, the function of Trx-1 translocation to the nucleus in cancer is not clear. In this study, we investigated t...

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Detalles Bibliográficos
Autores principales: Wu, Aihua, Fang, Daoquan, Liu, Yangyang, Shi, Xiaomeng, Zhong, Zuyue, Zhou, Baojian, Ye, Lechi, Sun, Xuecheng, Jiang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526669/
https://www.ncbi.nlm.nih.gov/pubmed/37771783
http://dx.doi.org/10.7150/thno.85460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526669/
https://www.ncbi.nlm.nih.gov/pubmed/37771783
http://dx.doi.org/10.7150/thno.85460

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