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FN1 mRNA 3'-UTR supersedes traditional fibronectin 1 in facilitating the invasion and metastasis of gastric cancer through the FN1 3'-UTR-let-7i-5p-THBS1 axis

Background: Current clinical treatments for gastric cancer (GC), particularly advanced GC, lack infallible therapeutic targets. The 3′-untranslated region (3′-UTR) has attracted increasing attention as a drug target. Methods: In vitro and in vivo experiments were conducted to determine the function...

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Detalles Bibliográficos
Autores principales: Pan, Siwei, Zhu, Jiaming, Liu, Pengfei, Wei, Qiaochu, Zhang, Siyu, An, Wen, Tong, Yuxin, Cheng, Zhenguo, Liu, Funan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526670/
https://www.ncbi.nlm.nih.gov/pubmed/37771777
http://dx.doi.org/10.7150/thno.82492